NCT03068767

The Relationship Between Vitamin D and Hepatitis B Virus Replication

Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 149 (actual)
• Sponsor: Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

149 HBV carriers with inadequate serum vitamin D levels were randomized to two groups: one is supplied with vitamin D and another without as controls. The markers of HBV replication were compared before and after treatment.

Detailed description

This is a randomized case-control trial. A total of 149 HBV carriers with inadequate vitamin D (\< 30 ng/mL) level were enrolled. They were randomly divided to two groups: one group receiving vitamin D supplement (1600 IU/day) for 2 months and another group as controls. The serum vitamin D, HBV DNA and qHBsAg levels were measured at baseline and after vitamin D supplement. Whether HBV DNA and qHBsAg have significant change after vitamin D supplement can be determined.

Conditions

• Vitamin D and Hepatitis B Virus

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin D

Timeline

• Start date: 2016-09-01
• Primary completion: 2019-01-01
• Completion: 2019-01-15
• First posted: 2017-03-03
• Last updated: 2020-02-12
• Results posted: 2020-02-12

Locations

1 site across 1 country: Taiwan