NCT03067818

Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: George Mason University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This study examines the effect of non-invasive brain stimulation targeting different brain areas on movement of the affected arm post-stroke. Participants will receive stimulation to each of 3 different brain areas combined with a session of arm exercise.

Detailed description

Small improvements in affected arm movement can be made with intensive physical practice. These improvements could potentially be enhanced by combining non-invasive brain stimulation with practice. To develop such an intervention, it is necessary to understand which brain areas should be stimulated in which types of patients. It is probably more beneficial to target one side of the brain vs. the other, for example, depending on the characteristics of the stroke. This study will examine the effect of stimulating one side of the brain vs. the other on the amount of improvement that occurs from physically practicing functional arm movements.

Conditions

• Stroke
• Hemiparesis
• Cerebral Vascular Accident
• Stroke, Ischemic

Interventions

Type	Name	Description
PROCEDURE	Unaffected Transcranial Magnetic Stimulation	Non-invasive brain stimulation to unaffected hemisphere site prior to practice
PROCEDURE	Affected Transcranial Magnetic Stimulation	Non-invasive brain stimulation to affected hemisphere site prior to practice
PROCEDURE	Control Transcranial Magnetic Stimulation	Non-invasive brain stimulation to control site prior to practice

Timeline

• Start date: 2017-06-20
• Primary completion: 2019-08-15
• Completion: 2019-08-28
• First posted: 2017-03-01
• Last updated: 2019-09-11

Locations

1 site across 1 country: United States