NCT03065504

Turmeric and Turmeric-containing Tablets and Sebum Production

Pilot Study on the Effects of Oral Turmeric and Turmeric-containing Tablets on Sebum Production

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

A noticeably increasing number of patients are asking for naturally based extracts and ingredients as supplementary dermatologic remedies. Patients are seeking natural and cost-effective skin care alternatives in place of prescription medications and procedures. This study will isolate the effects of oral turmeric and assess a combination tablet that includes turmeric on sebum production in healthy subjects.

Detailed description

Turmeric (Curcuma longa) is a spice that has been shown to exhibit anti-inflammatory, antimicrobial, antioxidant, anti-neoplastic properties, and even potential to improve mental illnesses. In western herbalism, Turmeric is primarily used as an anti-inflammatory agent. In India, turmeric is used in Ayurvedic medicine for the treatment of acne. It has been used both internally and externally. Curcumin is a phytochemical derived from turmeric and believed to be one of the key active components of turmeric. Curcumin is reported to have activity as an antibacterial and anti-inflammatory agent and has been used as a paste for skin eruptions and infections. Previous basic science work by Dr. Raja Sivamani's lab has shown that both turmeric and curcumin inhibit lipid synthesis in human sebocytes, the cells responsible for the production of sebum The goal of this study is to evaluate how ingestion of turmeric and tablets that have a combination of herbs including turmeric may modulate sebum production.

Conditions

• Skin Inflammation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Turmeric
DIETARY_SUPPLEMENT	Turmeric-containing combination tablet
DIETARY_SUPPLEMENT	Placebo tablets

Timeline

• Start date: 2016-11-01
• Primary completion: 2017-08-28
• Completion: 2017-08-28
• First posted: 2017-02-28
• Last updated: 2018-12-20

Locations

1 site across 1 country: United States