NCT03063892

Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion

Evaluating the Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion in Hip Fracture Patients

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Gregory M Georgiadis MD · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.

Conditions

• Hip Fractures

Interventions

Type	Name	Description
DRUG	Tranexamic Acid (TXA)	Tranexamic acid is an antifibrinolytic used to control bleeding
DRUG	Saline solution	Saline solution is used as the placebo comparator

Timeline

• Start date: 2017-08-30
• Primary completion: 2026-07-01
• Completion: 2026-09-01
• First posted: 2017-02-24
• Last updated: 2025-08-07

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study