NCT03063112

Radiofrequency and Chemical Neurolysis of Thoracic Splanchnic Nerve for Abdominal Cancer Pain

Comparative Study Between Radiofrequency Thermocoagulation and Chemical Neurolysis of Thoracic Splanchnic Nerve Bilaterally for the Management of Abdominal Cancer Pain

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 79 (estimated)
• Sponsor: South Egypt Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The study compares between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation and chemical neurolysis of bilateral thoracic splanchnic nerves in the management of refractory pain which developed in patients suffering from upper abdominal cancer.

Detailed description

Radiofrequency thermocoagulation of splanchnic nerves was done bilaterally at level of thoracic vertebra T10 and T11 ( there were no enough studies done to test the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation of splanchnic nerves at level of T10 ). Aim of the Study is to compare between the efficacy, safety and impact on the quality of life of radiofrequency thermocoagulation of bilateral thoracic splanchnic nerves at level T10 and T11 vertebra and chemical neurolytic block of them at level of T11 vertebra only in the management of upper abdominal cancer pain.

Conditions

• Abdominal Cancer

Interventions

Type	Name	Description
DEVICE	Radiofrequency generator device	sympathetic blockade or ablation of thoracic splanchnic nerves
DRUG	Lidocaine	sympathetic blockade or ablation of thoracic splanchnic nerves
DEVICE	C arm fluoroscopic device	sympathetic blockade or ablation of thoracic splanchnic nerves
DRUG	Ethyl alcohol	sympathetic blockade or ablation of thoracic splanchnic nerves

Timeline

• Start date: 2016-10-01
• Primary completion: 2017-04-10
• Completion: 2017-05-01
• First posted: 2017-02-24
• Last updated: 2017-02-28

Locations

1 site across 1 country: Egypt