Trials / Completed
CompletedNCT03059537
Validation of Stimulated ∆FGF19 for Diagnosing Bile Acid Diarrhoea
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 71 (actual)
- Sponsor
- Lars Kristian Munck · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This study aims to validate a possible diagnostic test for bile acid diarrhoea prospectively compared to the SeHCAT scintigraphy. Fasting participants are given a standard meal and 1,250 mg chenodeoxycholic acid. The investigators measure fasting FGF19, bile acids species including 7-alpha-CHO and serial blood samples after the stimulation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Oral chenodeoxycholic acid stimulation | oral intake of chenodeoxycholic acid to stimulate the ileal bile acid transporter and farnesoid X receptor |
Timeline
- Start date
- 2017-03-13
- Primary completion
- 2017-11-27
- Completion
- 2017-11-27
- First posted
- 2017-02-23
- Last updated
- 2017-12-12
Locations
5 sites across 1 country: Denmark
Source: ClinicalTrials.gov record NCT03059537. Inclusion in this directory is not an endorsement.