NCT03058055

Brain Exercises for Synaptic Plasticity

Brain Exercises for Synaptic Plasticity: the BEST Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: University of Kentucky · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The BEST study will investigate the feasibility of cognitive interventions in a randomized, placebo-controlled, clinical trial. The investigators will recruit 45 cognitively normal subjects and engage them in one of three cohorts over an 8 week period, including active reading vs. origami study arms and a placebo group without structured cognitive intervention.

Detailed description

This is a randomized, placebo controlled study investigating the practical implementation and conduct of two cognitive interventions in non-demented subjects. Subjects will be randomized 1:1:1 into three groups including: 1) a Book club that includes weekly one hour meetings and daily reading assignments, 2) Origami lessons (one hour/week) with daily take home Origami activities to complete, and 3) a placebo group with unstructured lifestyle activities (normal lifestyle activities without restraint).

Conditions

• Cognitive Change

Interventions

Type	Name	Description
BEHAVIORAL	Placebo	The placebo group will have unstructured lifestyle activities (normal lifestyle activities without restraint).
BEHAVIORAL	Origami	Origami lessons (one hour/week) with daily take home Origami activities to complete
BEHAVIORAL	Reading	Book club that includes weekly one hour meetings and daily reading assignments

Timeline

• Start date: 2016-07-15
• Primary completion: 2017-12-15
• Completion: 2017-12-15
• First posted: 2017-02-20
• Last updated: 2017-12-19

Locations

1 site across 1 country: United States