Trials / Completed
CompletedNCT03055442
Myo-inositol/D-chiro-inositol Ratio in Follicular Fluid
Altered Myo-inositol/D-chiro-inositol Ratio in Follicular Fluid of Women Undergoing in Vitro Fertilization Has Detrimental Effects on Oocyte and Embryo Quality
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 34 (actual)
- Sponsor
- Lo.Li.Pharma s.r.l · Industry
- Sex
- Female
- Age
- 18 Years – 28 Years
- Healthy volunteers
- Accepted
Summary
Considering the importance assumed by follicular microenvironment for a proper oocyte development, this study is a prospective observational clinical trial which aims to evaluate whether the embryo blastocyst quality may be affected by different Myo-inositol (MI) and D-chiro-inositol (DCI) levels in the follicular fluid (FF) of the aspired oocytes. The study includes egg donors and egg receiving couples participating in the oocyte donation program. MI/DCI is calculated in FF and related with blastocyst grade.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Dosage of myo-inositol | Quantitative analysis of myo-inositol was performed by gas chromatography-mass spectrometry (GC-MS) |
| OTHER | Dosage of D-chiro-inositol | Quantitative analysis of D-chiro-inositol was performed by gas chromatography-mass spectrometry (GC-MS) |
Timeline
- Start date
- 2016-10-01
- Primary completion
- 2016-11-01
- Completion
- 2016-12-01
- First posted
- 2017-02-16
- Last updated
- 2017-02-16
Locations
1 site across 1 country: Greece
Source: ClinicalTrials.gov record NCT03055442. Inclusion in this directory is not an endorsement.