Trials / Completed
CompletedNCT03055364
Cognitive Function After Treatment of Primary CNS Malignancy
Observational Study Evaluating Neurocognitive Function in Patients With Primary CNS Malignancy Receiving Radiation Treatment to the Brain
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 129 (actual)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 4 Years
- Healthy volunteers
- Not accepted
Summary
In this study, the investigators propose to evaluate cognitive function and determine the feasibility of neurocognitive assessment using a select CogState test battery in patients with primary intracranial malignancies receiving photon- or proton-based cranial irradiation with curative intent. The investigators will use the CogState software to quantify changes in verbal learning, memory, and executive function over the initial months and years following radiation treatment. Cognitive changes and temporal patterns of function will be compared to baseline performance for each patient. Data regarding cognitive function, fatigue, quality of life, and standard patient reported outcomes will be collected to characterize the daily impact of treatment. In addition, observed outcomes will be correlated with dosimetry values, radiation dose volumes, and anatomic dose distribution.
Conditions
Timeline
- Start date
- 2017-06-13
- Primary completion
- 2023-11-02
- Completion
- 2023-11-02
- First posted
- 2017-02-16
- Last updated
- 2024-05-10
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03055364. Inclusion in this directory is not an endorsement.