NCT03053999

Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 53 (estimated)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The study aims to identify predictors of disease in patients with hyperparathyroidism (HPTH) who undergo surgery.

Detailed description

Researchers aim to identify somatic mutations and inherited genetic variants which may help predict the development of PNET in patients with hyperparathyroidism.

Conditions

• Multiple Endocrine Neoplasia
• Pancreatic Neuroendocrine Tumors
• Hyperparathyroidism

Interventions

Type	Name	Description
OTHER	Genome Sequencing	Analyses includes genome sequencing based analysis to identify novel germline variations in blood DNAs and somatic changes in tumor DNAs, which may contribute to the development of pancreatic tumors.
OTHER	Data Review	Clinical information retrieved from the patients' medical record including: de-identified demographic data (age, gender, race/ethnicity), medical history, family history, disease status, treatment response, survival information, and selected clinical data from medical record (calcium levels, calcitonin levels).

Timeline

• Start date: 2012-10-09
• Primary completion: 2022-10-01
• Completion: 2023-10-01
• First posted: 2017-02-15
• Last updated: 2019-09-12

Locations

1 site across 1 country: United States