NCT03052621

Revisiting Omental Transposition in Locally Advance and Locally Recurrent Breast Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Queen Sirikit Centre for Breast Cancer · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Locally advance breast cancer and extensive locoregional recurrence are still considered as complexity of reconstruction. Although previous studies concluded that omental transposition was considerably indicated in poor vascularity in irradiated tissue, secondary infection and large defect become the obstacles of local tissue flaps. While some centres showed the excellent healing of omental transposition. Meanwhile, many studies showed the preferable outcome in escalating radiotherapy in term of locoregional control. In the investigators' institute, omental transposition in breast cancer has been developed for twenty years. The only institute in Thailand enhanced using this procedure in order to closure of large primary breast cancer and chest wall recurrence. This procedure is undertaken by single surgeon (Dr. K.J.). The investigators' protocol of omental transposition is including preoperative chemotherapy, preoperative accelerated radiation up to 80 Gy, approval of breast cancer centre committee, and meticulous wound care including vacuum assisted wound dressing, non-adhesive dressing. As a result, survival time could be improved.

Conditions

• Survival Rate

Interventions

Type	Name	Description
PROCEDURE	Omental transposition	Harvesting the omentum to cover irradiated defects of breast cancer

Timeline

• Start date: 1994-01-01
• Primary completion: 2016-10-01
• Completion: 2016-12-01
• First posted: 2017-02-14
• Last updated: 2017-02-14

Locations

1 site across 1 country: Thailand