Clinical Trials Directory

Trials / Completed

CompletedNCT03048006

Post-marketing Surveillance Study for Evaluation of Dotarem Safety

Evaluation of Dotarem Safety

Status
Completed
Phase
Study type
Observational
Enrollment
44,456 (actual)
Sponsor
Guerbet · Industry
Sex
All
Age
100 Years
Healthy volunteers
Accepted

Summary

Guerbet conducted a non-interventional post-marketing surveillance study on its Magnetic Resonance Imaging (MRI) contrast agent Dotarem (gadoteric acid/gadoterate meglumine). The aim of this study, which was conducted in accordance with section 67, paragraph 6 of the German drug regulation, Arzneimittelgesetz, was to gain additional insights into the diagnostic efficacy, reliability and safety of Dotarem in routine practice using the most up-to-date MRI techniques and application methods.

Detailed description

Diagnostic efficacy was assessed by the following endpoints: diagnostic value ("yes"/"no") and imaging quality (5-step scale from "excellent" to "very poor"). Safety was evaluated on the basis of the frequency and seriousness of adverse events that occurred following Dotarem injection.

Conditions

Interventions

TypeNameDescription
PROCEDUREMRI with Dotarem

Timeline

Start date
2011-01-01
Primary completion
2013-12-01
Completion
2013-12-01
First posted
2017-02-09
Last updated
2017-05-02
Results posted
2017-05-02

Source: ClinicalTrials.gov record NCT03048006. Inclusion in this directory is not an endorsement.