NCT03046836

Oxytocin, Alcohol Craving, and Intimate Partner Aggression

Effects of Oxytocin on Alcohol Craving and Intimate Partner Aggression

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Alcohol use disorders (AUD) and intimate partner aggression (IPA) frequently co-occur. There are significant health and economic burdens associated with AUD and co-occurring IPA, and little empirical data to guide treatment efforts. The neuropeptide oxytocin may help mitigate both AUD and IPA. However, clinical data examining oxytocin's effects on human aggression is scant. The proposed study is designed to address these gaps in the literature by utilizing a human laboratory paradigm to test the effects of oxytocin on craving and aggression among couples with AUD and co-occurring IPA.

Conditions

• Alcohol Use

Interventions

Type	Name	Description
DRUG	Oxytocin	40 IU oxytocin nasal spray
DRUG	Placebo	Saline

Timeline

• Start date: 2017-07-01
• Primary completion: 2021-04-11
• Completion: 2021-04-11
• First posted: 2017-02-08
• Last updated: 2022-05-09
• Results posted: 2022-05-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study