Trials / Unknown
UnknownNCT03046511
Peritonitis Prevention After Insertion of Peritoneal Dialysis Catheter.
Comparison Between Post - Surgical Intraperitoneal Antibiotics Administration Vs. Intravenous Pre- Surgical Administration for the Prevention of Peritonitis After Insertion of Peritoneal Dialysis Catheter in Peritoneal Dialysis Patients
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Carmel Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
An intraperitoneal implanted catheter is always necessary to perform Peritoneal Dialysis. Catheter insertion has been associated with infectious complication such as Exit Site Infection (ESI), Tunnel Infection and Peritonitis. The last one may lead to loss of the technique because the need of catheter removal. Most of international guidelines recommends the use of prophylactic antibiotics. Different protocols has been used, mostly intravenous single injection before the procedure. For the last 25 years our unit gives a single intraperitoneal dose of Cefazolin immediately after the catheter insertion. The aim of this study is compare the effect of a pre- operative IV dose os Cefazolin with a post- procedure intraperitoneal single dose administration of the same drug.
Conditions
- Peritoneal Dialysis-associated Peritonitis
- Peritoneal Dialysis Catheter Infection
- Peritoneal Dialysis Complication
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Cefazolin | A post- procedure administration of Cefazolin will be compared with a pre-operative intravenous dose |
Timeline
- Start date
- 2017-03-08
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
- First posted
- 2017-02-08
- Last updated
- 2023-02-13
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT03046511. Inclusion in this directory is not an endorsement.