NCT03046147

The Effect of Roux-en-Y Gastric Bypass on Bone Turnover

Bone Mineral Density and Markers of Bone Turnover After Roux-en-Y Gastric Bypass

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 20 (estimated)
• Sponsor: Hvidovre University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Bone mineral density (BMD) is decreased after Roux-en-Y gastric bypass (RYGB) but whether RYGB induces changes in BMD beyond adaptation to major weight loss is not known. We aim to investigate BMD changes in weight bearing (hip, lumbal columna) and in non-weight bearing (forearm) regions before and after maximal weight loss at 1 year and after weight stabilisation at 4 years after RYGB. Moreover, plasma markers of bone turnover will be studied at fasting and during oral glucose tolerance test.

Conditions

• Gastric Bypass Surgery
• Obesity
• Bone Loss

Interventions

Type	Name	Description
PROCEDURE	Roux-en-Y gastric bypass	Roux-en-Y gastric bypass surgery for morbid obesity

Timeline

• Start date: 2015-09-01
• Primary completion: 2017-05-01
• Completion: 2017-09-01
• First posted: 2017-02-08
• Last updated: 2017-02-08

Locations

1 site across 1 country: Denmark