NCT03045744

Long-term PAS in Rehabilitation After SCI

Long-term Paired Associative Stimulation in Rehabilitation of Spinal Cord Injury Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 5 (actual)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators have recently shown in two pilot incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles (1). In this study, the investigators will administer long-term paired associative stimulation to incomplete SCI patients in a long-term manner, keeping each patient in the study for as long as continuous improvement is observed.

Conditions

• Spinal Cord Injuries

Interventions

Type	Name	Description
DEVICE	long-term paired associative stimulation	Paired associative stimulation (PAS) administered 3 times per week. PAS comprises transcranial magnetic stimulation (eXimia magnetic stimulator, Nexstim Ltd, Helsinki, Finland) and peripheral nerve stimulation (given with Dantec Keypoint® electroneuromyography device (Natus Medical Incorporated, Pleasanton, CA, USA)).

Timeline

• Start date: 2017-02-10
• Primary completion: 2023-06-01
• Completion: 2023-12-01
• First posted: 2017-02-07
• Last updated: 2025-05-13

Locations

1 site across 1 country: Finland