NCT03044340

Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner and QST

Vascular and Neurologic Exploration of Small Nervous Fiber by Sudoscanner

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: Fondation Hôpital Saint-Joseph · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest. The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.

Conditions

• Erythermalgia

Interventions

Type	Name	Description
OTHER	impedance measurement and pain evaluation	Measurement of chlorine ions impedance by SUDOSCAN and pain due to temperature evaluation with THERMOTEST

Timeline

• Start date: 2017-01-12
• Primary completion: 2018-01-18
• Completion: 2019-04-17
• First posted: 2017-02-07
• Last updated: 2019-04-25

Locations

1 site across 1 country: France