NCT03042169

Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer

Surgical Resection Plus Chemotherapy Versus Chemotherapy Alone in Oligometastatic Stage IV Gastric Cancer - a Multicenter, Prospective, Open-labeled, Two-armed, Randomized, Controlled Phase III Trial

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: University Hospital, Lille · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Surgical resection of the primary tumour and treatment of the metastatic site in oligometastatic stage IV metastatic gastric adenocarcinoma enhances survival and improves quality of life with acceptable postoperative morbidity and mortality in a selected group of operable patients with only one metastatic site that does not progress under chemotherapy.

Conditions

• Gastric Adenocarcinoma

Interventions

Type	Name	Description
DRUG	Preoperative Chemotherapy	Standard chemotherapy regiments according to risk of recurrence
PROCEDURE	Surgery	the surgical treatment will undergo gastrectomy between D1 and D30 after randomization.
DRUG	Postoperative chemotherapy	Chemotherapy should be restarted between D1 and D30 post-randomization

Timeline

• Start date: 2021-08-25
• Primary completion: 2024-08-28
• Completion: 2024-08-28
• First posted: 2017-02-03
• Last updated: 2025-12-23

Locations

1 site across 1 country: France