NCT03041532

Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme

Impact of Proximal Colon Retroflexion in Colorectal Cancer Screening Programme: Randomized Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 692 (actual)
• Sponsor: Hospital del Rio Hortega · Academic / Other
• Sex: All
• Age: 50 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

Colorectal cancer (CRC) is the most common tumor and the second leading cause of death in the Western world. The decrease in incidence and mortality by CRC in the population undergoing screening has been observed. Colonoscopy is the recommended method for detecting tumors in early stages, as well as identifying and resecting adenomatous polyps, which are the precursor lesions of most CRCs. Colonoscopy should be of high quality to decrease incidence and mortality by CRC and avoid interval cancer. The literature shows that colonoscopy does not prevent right colon lesions in the same way as the left colon lesions, with most of the interval cancers located in the right colon. Studies published so far show an increase in the adenomas detection rate (ADT) in the right colon in the second visualization of this segment and an increase between 2 and 10% if this second examination is performed with the proximal retroflexion maneuver.Retroflexion is a safe maneuver in expert endoscopists. The aim of our study is to evaluate the ADT in the right colon by means of a second visualization by performing proximal retroflexion or second frontal visualization at random in the CCR screening population.

Conditions

• Colorectal Neoplasms
• Adenoma Detection Rate

Interventions

Type	Name	Description
PROCEDURE	Proximal retroflexion	The investigator explore twice right colon, first front view and second forward viewing or proximal retroflexion depends on randomization
PROCEDURE	Frontal view	The investigator explore twice right colon with frontal viewing

Timeline

• Start date: 2017-10-01
• Primary completion: 2018-10-30
• Completion: 2018-11-30
• First posted: 2017-02-02
• Last updated: 2020-02-19

Locations

1 site across 1 country: Spain