NCT03039556

Step-reduction in Older Men and Women

The Influence of Acute Physical Inactivity on Metabolic Function in Older Men and Women

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: McMaster University · Academic / Other
• Sex: All
• Age: 65 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This study investigates the effects of two weeks of reduced daily ambulation and a subsequent return to normal physical activity on metabolic health of older adults.

Detailed description

Aging results in a progressive loss of muscle mass that is accelerated by periods of muscular disuse, common for older adults during hospitalization or convalescence from illness. Transient physical inactivity has been shown to cause muscular atrophy and impairments in insulin sensitivity in both younger and older adults. However, the recovery capacity of older adults after such physical inactivity remains unknown. This study aims to determine the impact of two weeks of daily step reduction to ≤1000 steps per day, an experimental model mimicking short-term physical inactivity, on glycemic control in older adults and further investigate whether older adults are able to recover from the consequences of this inactivity simply by returning to their habitual activity for 14 days.

Conditions

• Older Adults
• Reduced Physical Activity

Interventions

Type	Name	Description
BEHAVIORAL	Normal Daily Steps	Complete normal daily ambulation for one week
BEHAVIORAL	Step-Reduction	Reduce daily ambulation to fewer than 1000 steps per day for two weeks
BEHAVIORAL	Return to Normal Daily Steps	Increase daily ambulation to 100% of normal daily step-count for two weeks

Timeline

• Start date: 2015-09-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2017-02-01
• Last updated: 2017-02-01

Locations

1 site across 1 country: Canada