NCT03036202

Pharmacokinetics of Epinephrine During Cardiac Arrest

Pharmacokinetic Study of Epinephrine During Cardiac Arrest Determining T1/2 and Time to Peak Concentration

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: Haukeland University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

To determine the pharmacokinetics of epinephrine during cardiac arrest.

Detailed description

The aim of out study is to determine the pharmacokinetics in humans during cardiac arrest, following a single dose of epinephrine. Venous samples will be withdrawn every minute the first five minutes following a single dose. The aim of the study is to determine T1/2 in a clinical setting and to determine time to peak concentration.

Conditions

• Cardiac Arrest

Interventions

Type	Name	Description
DRUG	Epinephrine	This is truly an observational study to determine T1/2 for epinephrine and time to peak concentration following a single dose of epinephrine in a cardiac arrest setting

Timeline

• Start date: 2017-06-26
• Primary completion: 2018-07-12
• Completion: 2018-10-12
• First posted: 2017-01-30
• Last updated: 2019-08-21

Locations

1 site across 1 country: Norway

Regulatory

• FDA-regulated drug study