NCT03035799

Comparing Two Types of Diets on Psychological and Gastrointestinal Symptoms

A Randomized Trial Comparing Two Types of Diets on Psychological and Gastrointestinal Symptoms

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This pilot study proposes to gain a better understanding of the health benefits of the popular "paleo-diet" in patients with irritable bowel syndrome (IBS) and explore underlying mechanisms of benefit.

Detailed description

In the proposed study, the primary hypothesis is that, compared with a customary diet, consumption of a paleo-diet will improve psychological and gastrointestinal symptoms in patients with irritable bowel syndrome. Investigators also hypothesize consumption of the Paleolithic diet will result in decreased intestinal permeability, decreased inflammatory markers, and changes in the gut microbiome and microbiologic profiles.

Conditions

• Irritable Bowel Syndrome

Interventions

Type	Name	Description
OTHER	Paleolithic diet	Paleolithic diet
OTHER	General Healthful Diet	General Healthful Diet

Timeline

• Start date: 2018-04-24
• Primary completion: 2020-04-01
• Completion: 2020-04-01
• First posted: 2017-01-30
• Last updated: 2020-05-07

Locations

1 site across 1 country: United States