NCT03035084

Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?

Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena? A Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: King Faisal Specialist Hospital & Research Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Several studies have demonstrated that D2 treatment is associated with a decrease in 25(OH)D3 level and therefore have proposed that D3 would be preferable in term of raising total 25(OH)D level. The investigators postulate that the D2 treatment-associated decrease in 25(OH)D3 level may be related to an increase in total 25(OH)D level rather than being specific to D2 treatment, and thus there would be a D3 treatment-associated decrease in 25(OH)D2 level. The investigators plan to conduct a double-blind placebo-controlled trial to examine the effect of D3 treatment on 25(OH)D2 level and the effect of D2 treatment on 25(OH)D3 leve

Conditions

• Vitamin D Deficiency
• 25-Hydroxyvitamin D Concentration

Interventions

Type	Name	Description
DRUG	Vitamin D3	Single oral dose of 50,000 IU of vitamin D3
DRUG	Vitamin D2	Single oral dose of 50,000 IU of vitamin D2
DRUG	Placebo oral capsule	Placebo oral capsule

Timeline

• Start date: 2017-02-15
• Primary completion: 2017-11-20
• Completion: 2017-11-20
• First posted: 2017-01-27
• Last updated: 2018-08-13

Locations

1 site across 1 country: Saudi Arabia