NCT03035045

Oral Paracetamol Premedication Effect on Maternal Pain in Amniocentesis

Oral Paracetamol Premedication Effect on Maternal Pain in Amniocentesis: A Randomized Double Blind Placebo-controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: Department of Medical Services Ministry of Public Health of Thailand · Other Government
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

This randomized controlled trial, compares perioperative and postoperative pain score by using visual analog scale in pregnant women undergoing amniocentesis. The experimental group will be given oral paracetamol premedication whereas the controlled group will be given oral placebo premedication.

Detailed description

Perioperative and postoperative amniocentesis are often painful which cause concerns to those who has to undergo amniocentesis. Anxiety is one of the factor that may prolong operative time, resulting in an increase risk of complication from the procedure. Furthermore, pregnant women, in order to relief the pain, might require others drugs, which has both maternal and fetal side effect. So In conclusion, this study aims to compare efficacy of oral paracetamol premedication and oral placebo premedication by using visual analog scale to evaluate pain.

Conditions

• Amniocentesis

Interventions

Type	Name	Description
DRUG	Paracetamol
DRUG	Placebo Oral Tablet

Timeline

• Start date: 2016-11-01
• Primary completion: 2017-06-01
• Completion: 2017-07-01
• First posted: 2017-01-27
• Last updated: 2017-01-27

Locations

1 site across 1 country: Thailand