Trials / Completed
CompletedNCT03031743
The Influence of the Microbiome on Rotavirus Vaccine Immunogenic Response in Infants in Karachi, Pakistan
Nested Case-control Analysis of the Influence of the Microbiome on Rotavirus Vaccine Immunogenic Response in Infants in Karachi, Pakistan
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 88 (actual)
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Academic / Other
- Sex
- All
- Age
- 6 Weeks – 3 Years
- Healthy volunteers
- Accepted
Summary
This is a nested case-control study within an ongoing rotavirus vaccine immunogenicity trial in Karachi, Pakistan. The primary study aim is to compare the fecal microbiota composition and diversity of infants who do (control) and do not (case) demonstrate immune seroconversion to rotavirus vaccination. The infants will be matched for vaccination dose, age and breast-feeding practices.
Conditions
Timeline
- Start date
- 2014-01-01
- Primary completion
- 2015-02-01
- Completion
- 2015-07-01
- First posted
- 2017-01-26
- Last updated
- 2017-01-26
Locations
1 site across 1 country: Pakistan
Source: ClinicalTrials.gov record NCT03031743. Inclusion in this directory is not an endorsement.