NCT03031613

Effects of PEEP on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy

Effects of Positive End Expiratory Pressure (PEEP) on Intracranial and Intraocular Pressure in Robot-assisted Laparoscopic Radical Prostatectomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Gangnam Severance Hospital · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Accepted

Summary

To investigate the effects of positive end-expiratory pressure (PEEP) on the intracerebral pressure (ICP) and intraocular pressure (IOP) in patients undergoing robot assisted laparoscopic radical prostatectomy (RALRP)

Detailed description

Application of PEEPmay reduce pulmonary complication following RALRP. Meanwhile, it may increase ICP and IOP, which has been debated for decades. Moreover, Trendelenburg position and pneumoperitoneum, which are mandatory for RALRP, may augment elevation of ICP and IOP. This study aims to investigate the effects of PEEP on the ICP and IOP in patients undergoing RALRP.

Conditions

• Prostate Cancer

Interventions

Type	Name	Description
PROCEDURE	PEEP group	Application of 5cmH20 positive end expiratory pressure
PROCEDURE	ZEEP group	No application of positive end expiratory pressure

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-11-01
• Completion: 2017-11-01
• First posted: 2017-01-25
• Last updated: 2017-01-25

Locations

1 site across 1 country: South Korea