NCT03030807

Pulmonary Hypertension in Hypersensitivity Pneumonitis

Recognition of Pulmonary Hypertension in Patients With Hypersensitivity Pneumonitis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 426 (actual)
• Sponsor: Medical University of Graz · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The investigation serves the identification of pulmonary hypertension (PH) among patients with hypersensitivity pneumonitis (HP). The exact prevalence of PH in HP is unknown. Data from South America indicate that the prevalence of pre-capillary PH amongst patients with HP is higher than 20%. There are no reliable data from Europe so far. According to the investigators previous analysis, more than 400 HP patients have participated in pulmonary rehabilitation at least once in the past 10 years at Klinikum Bad Gleichenberg (Rehabilitation Center for Agricultural Workers in Austria). This collective of patients is to be invited to participate in the study. A diagnostic algorithm will be applied in the clinical trial, in the case of clinical suspicion the diagnosis of PH will be confirmed by right heart catheterization. Besides the determination of the prevalence of PH in patients with HP the investigators aim to assess the reliability of non-invasive methods (e.g. Echocardiography, ECG...) to predict PH.

Conditions

• Pulmonary Hypertension

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Right heart catheterization (in case of suspected PH)

Timeline

• Start date: 2016-10-01
• Primary completion: 2020-10-31
• Completion: 2020-10-31
• First posted: 2017-01-25
• Last updated: 2020-11-19