NCT03029416

Two Radiation Dose Schedules of SBRT to Lung Metastases < 5cm in Dimension

A Randomized Phase 2 Study of Two Radiation Dose Schedules of Stereotactic Body Radiotherapy (SBRT) to Lung Metastases < 5cm in Dimension

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Ronald McGarry · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

30 Gy single fraction of SBRT for lung metastases will result in comparable oncologic outcomes to 18Gy in three fractions (or dosing to a BED \</-100Gy at the discretion of the radiation oncologist) with respect to disease control and toxicity.

Detailed description

Using two different doses of SBRT, this study will examine the 6-month local disease control rate (LDCR) of the SBRT-treated metastasis to determine the optimum dosing for SBRT in pulmonary metastases. This will allow us to establish baseline SBRT data, from which we will develop a second trial to examine sequencing of immunotherapy with SBRT.

Conditions

• Neoplasm Metastasis
• Cancer
• Radiation Therapy Complication

Interventions

Type	Name	Description
RADIATION	Stereotactic Body Radiation Therapy	Stereotactic Body Radiation Therapy using different fractionation schedules

Timeline

• Start date: 2017-10-26
• Primary completion: 2018-07-20
• Completion: 2018-08-09
• First posted: 2017-01-24
• Last updated: 2018-10-15

Locations

1 site across 1 country: United States