Trials / Unknown
UnknownNCT03027011
Remote Ischemic Preconditioning on Brain Injury in Carotid Endarterectomy
Effect of Remote Ischemic Preconditioning on Brain Injury in Carotid Endarterectomy
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University · Academic / Other
- Sex
- All
- Age
- 55 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This is a randomized controlled trial designed to test an intervention (Remote ischemic preconditioning) in patients undergoing carotid endarterectomy (CEA).Remote ischemic preconditioning(RIPC) with transient upper limb ischemia/reperfusion is a novel, simple, cost-free,non-pharmacological and non-invasive strategy.The purpose of this study is to evaluate the effects of Remote Ischaemic Preconditioning on perioperative ischaemic injury in patients undergoing carotid endarterectomy compared to control intervention.The outcomes of interest include neurocognitive function,clinical outcomes,and biomarkers of brain injury.
Detailed description
Remote ischemic preconditioning (RIPC) protocol will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood pressure cuff inflated to a pressure 200mmHg
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Remote Ischemic Preconditioning | RIPC will be induced during anesthesia by 3 cycles of 5-min upper limb ischemia and 5-min reperfusion using a blood-pressure cuff inflated to a pressure 200mmHg |
| PROCEDURE | Control | Control group without remote ischemic preconditioning |
Timeline
- Start date
- 2017-03-01
- Primary completion
- 2017-12-01
- Completion
- 2017-12-01
- First posted
- 2017-01-20
- Last updated
- 2017-03-10
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03027011. Inclusion in this directory is not an endorsement.