Trials / Unknown
UnknownNCT03026946
Alitretinoin vs Cyclosporine in Severe Recurrent Vesicular Hand Eczema
Efficacy of Oral Alitretinoin Versus Oral Cyclosporine in Patients With Severe Recurrent Vesicular Hand Eczema. A Randomized Prospective Open-label Trial With Blinded Outcome Assessment
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 76 (estimated)
- Sponsor
- University Medical Center Groningen · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare the efficacy of alitretinoin and cyclosporine in the treatment of patients with severe recurrent vesicular hand eczema.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Alitretinoin | Oral alitretinoin capsule of 30mg once daily for a total of 24 weeks. |
| DRUG | cyclosporin A | Oral cyclosporine A start dose 5 mg/kg/day (split in 2 doses), decreasing the dose after 8 weeks to 3 - 3.5 mg/kg/day (split in 2 doses). The treatment period is 24 weeks. |
Timeline
- Start date
- 2017-05-29
- Primary completion
- 2022-07-01
- Completion
- 2022-07-01
- First posted
- 2017-01-20
- Last updated
- 2019-02-26
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT03026946. Inclusion in this directory is not an endorsement.