Trials / Unknown
UnknownNCT03026907
Alitretinoin vs Azathioprine in Severe Non-hyperkeratotic Hand Eczema
Efficacy of Oral Alitretinoin Versus Oral Azathioprine in Patients With Severe Chronic Non-hyperkeratotic Hand Eczema. A Randomized Prospective Open-label Trial With Blinded Outcome Assessment
- Status
- Unknown
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 116 (estimated)
- Sponsor
- University Medical Center Groningen · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare the efficacy of alitretinoin and azathioprine in the treatment of patients with severe chronic non-hyperkeratotic hand eczema.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Alitretinoin | Oral alitretinoin capsule of 30mg once daily for a total of 24 weeks. |
| DRUG | Azathioprine | Oral azathioprine tablets twice daily in a dose of 1.5 or 2.5mg/kg/day, depending on the thiopurine methyltransferase (TPMT) activity. |
Timeline
- Start date
- 2016-05-01
- Primary completion
- 2019-12-01
- Completion
- 2019-12-01
- First posted
- 2017-01-20
- Last updated
- 2018-05-04
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT03026907. Inclusion in this directory is not an endorsement.