NCT03024229

Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine

The Importance of Metabolomics in Assessing the Quality of Kidney Transplants Retained on a LifePort® Perfusion Machine Before Renal Transplantation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University Hospital, Tours · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

When the kidneys are perfused on perfusion machines before transplantation, the resistance parameters as well as the histological score on the pre-implantation biopsy participate in the evaluation of the quality of the graft. The metabolomic profile of the infusion fluid could provide additional evidence.

Detailed description

The quality of the renal transplant prior to transplantation is essential for the recovery of graft function in the days following transplantation and its long-term survival. When the kidneys are perfused on perfusion machines before transplantation, the resistance parameters as well as the histological score on the pre-implantation biopsy participate in the evaluation of the quality of the graft. The metabolomic profile of the infusion fluid could provide additional evidence.

Conditions

• Renal Transplantation

Interventions

Type	Name	Description
DEVICE	LifePort® perfusion machine	Renal perfusion on LifePort® machine

Timeline

• Start date: 2017-03-15
• Primary completion: 2019-09-15
• Completion: 2020-01-14
• First posted: 2017-01-18
• Last updated: 2025-12-23

Locations

2 sites across 1 country: France