NCT03020758

Effect of Dried Fruit on Cardiometabolic Risk Factors

The Effect of Bioactives in Dried Plums, Figs, Dates, and Raisins Compared With a High Carbohydrate Snack on Risk Factors for Cardiometabolic Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 55 (actual)
• Sponsor: Penn State University · Academic / Other
• Sex: All
• Age: 25 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This is a 2-period randomized crossover study with free-living subjects on self-selected diets. The objective of this study is to compare the effects of ¾ cup of a blend of dried plums, figs, dates and raisins (DPFDR) with an isocaloric and macronutrient matched snack food on blood pressure, vascular health and lipids and lipoproteins in 50 participants who are representative of the U.S. population and at risk for cardiovascular disease (overweight/obese, elevated LDL-cholesterol, prehypertension, and/or prediabetes). The investigators hypothesize that the inclusion of DPFDR in the diet will decrease blood pressure and LDL-cholesterol, and improve artery function (assessed by standard blood pressure measure, 24 hr ambulatory blood pressure, central blood pressure and arterial stiffness) compared to the control group and baseline.

Conditions

• Cardiovascular Diseases
• Metabolic Syndrome

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dried Fruit	Mixture of equal parts 4 dried fruits (figs, raisins, dates, plums) totaling 3/4 cup daily.
OTHER	High Carbohydrate Snack	Calorie-matched carbohydrate-rich snack.

Timeline

• Start date: 2017-02-01
• Primary completion: 2018-11-30
• Completion: 2018-11-30
• First posted: 2017-01-13
• Last updated: 2023-08-18

Locations

1 site across 1 country: United States