Trials / Completed
CompletedNCT03020108
Serum Caspase 3, Annexin a2 and Soluble Fas Levels and Endometriosis
The Relation Between Serum Caspase 3, Annexin a2 and Soluble Fas Levels and Severity of Endometriosis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 90 (actual)
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Other Government
- Sex
- Female
- Age
- 15 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
The study population will comprise of 90 women age varying between 15-55 years, those are candidate for laparoscopic surgery due to definition of \>4 cm endometrioma or any other benign ovarian cysts such as mature teratoma or simple serous cysts on ultrasound examination, chronic pelvic pain, infertility. The blood samples will be drawn for analysis of serum biomarkers.
Detailed description
The participants will be accepted for the study between 1st of August 2016 to 30th June 2017. 2 cc blood samples will be drawn from the antecubital vein for serum analysis of caspase 3, annexin a2 and soluble fas levels before the operations. The patients will divide into three groups. The group 1 will comprise of 30 patients with benign ovarian cysts such as mature teratoma or simple serous cysts on ultrasound examination. The group 2 will comprise of 30 patients with diagnosis of stage 1-2 endometriosis in guidance with the revised American Society for Reproductive Medicine classification. The group 3 will comprise of 30 patients with diagnosis of stage 3-4 endometriosis in guidance with the revised American Society for Reproductive Medicine classification. The blood samples will be kept in -80 C degree after centrifuge till at the end of the study.The relation between serum caspase 3, annexin a2 and soluble fas levels and severity of endometriosis will be analysed.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Blood sample | 2 cc blood samples will be drawn from antecubital vein |
Timeline
- Start date
- 2016-08-01
- Primary completion
- 2017-06-01
- Completion
- 2017-08-01
- First posted
- 2017-01-13
- Last updated
- 2017-08-28
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT03020108. Inclusion in this directory is not an endorsement.