NCT03018613

Fecal Microbiota Transplantation for Chronic Functional Constipation

Evaluation of the Effect of Fecal Microbiota Transplantation on Chronic Functional Constipation and Its Mechanism

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: First Affiliated Hospital of Chengdu Medical College · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Chronic functional constipation is a common digestive system disease, the incidence is increasing in recent years.It is reported that the occurrence and development of chronic functional constipation is closely related to imbalance of intestinal flora .Moreover,types and quantity of intestinal flora may be related to intestinal motility. Fecal microbiota transplantation as a new technology to rebuild intestinal flora has been used for several disease，but the clinical efficacy of chronic functional constipation by fecal microbiota transplantation needs to be further explored.

Detailed description

Patients who meet the inclusion crit chronic functional constipation will be separated into two parts depending on acceptation or refuse of Fecal microbiota transplantation.Blood specimen from patients will be collected to analysis intestinal motility.

Conditions

• Chronic Functional Constipation
• Intestinal Bacteria Flora Disturbance
• Fecal Microbiota Transplantation

Interventions

Type	Name	Description
OTHER	Fecal Microbiota Transplantation	Fecal Microbiota Transplantation and the traditional treatments for chronic functional constipation in part 1.
OTHER	Normal Saline	Normal saline and the traditional treatments for chronic functional constipation in part 2

Timeline

• Start date: 2016-07-01
• Primary completion: 2018-07-01
• Completion: 2019-07-01
• First posted: 2017-01-12
• Last updated: 2017-01-12

Locations

1 site across 1 country: China