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Active Not RecruitingNCT03018418

Proton Therapy in Reducing Toxicity in Anal Cancer

A Prospective Pilot Study to Evaluate the Feasibility of Intensity Modulated Proton Therapy in Reducing Toxicity in Anal Cancer

Status
Active Not Recruiting
Phase
Phase 2
Study type
Interventional
Enrollment
14 (actual)
Sponsor
Jordan Kharofa · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to determine whether the amount of radiation given to the normal areas around the anal cancer can be reduced by using Proton Therapy while reducing the side effects that are seen with standard therapy.

Conditions

Interventions

TypeNameDescription
RADIATIONProton therapyPrimary target volume 50.4-54 CGE in 28-30 fractions; Nodal volumes 42-54 CGE in 28-30 fractions
DRUGChemotherapy5FU 1000 mg/m2/day as 96 hour infusion days 1-5 and 29-33; Mitomycin 10mg/m2 days 1 and 29

Timeline

Start date
2017-01-04
Primary completion
2022-04-07
Completion
2025-07-01
First posted
2017-01-12
Last updated
2024-09-19
Results posted
2023-10-05

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03018418. Inclusion in this directory is not an endorsement.