NCT03015974

Registry of IgA Nephropathy in Chinese Children

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 1,200 (estimated)
• Sponsor: Peking University First Hospital · Academic / Other
• Sex: All
• Age: 1 Month – 18 Years
• Healthy volunteers: Not accepted

Summary

This study tries to identify the safe and effective treatment option for IgA nephropathy in children. Investigators will perform prospective registration study among 25 pediatric nephrology medical centers in China.

Detailed description

A total of 1200 patients diagnosed as primary IgA nephropathy with nephrotic proteinuria will be enrolled among 25 pediatric nephrology medical centers nationwide, according to the following protocol. 1. Establishment of registration database online. 2. Participants will be enrolled according to the inclusion criteria and exclusion criteria. 3. The following data will be collected prospectively, including demographic data, clinical symptoms, physical examination, laboratory examination, renal pathology, treatment protocol and follow-up. 4. SPSS software (version 14.0; SPSS, Inc., Chicago, IL, USA) will be used for statistical analysis. P value less than 0.05 will be considered significant.

Conditions

• IgA Nephropathy
• Proteinuria in Nephrotic Range
• Immunosuppressive Treatment

Interventions

Type	Name	Description
DRUG	Corticosteroid
DRUG	Cyclophosphamide
DRUG	Mycophenolate mofetil
DRUG	Dipyridamole
DRUG	ACE Inhibitor or Angiotensin receptor antagonist

Timeline

• Start date: 2016-01-01
• Primary completion: 2024-12-01
• Completion: 2024-12-01
• First posted: 2017-01-10
• Last updated: 2023-12-06

Locations

1 site across 1 country: China