Trials / Unknown
UnknownNCT03014882
Sperm DNA Damage in β-thalassemia Major: Is There a Role for Antioxidants?
- Status
- Unknown
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- Ain Shams University · Academic / Other
- Sex
- Male
- Age
- 16 Years
- Healthy volunteers
- Accepted
Summary
Accumulation of iron in patients with beta thalassemia major causes free radical formation which leads to damage of biological membranes. Sperm DNA damage may result from these generated antioxidants. We aimed at investigating the current DNA damage in the sperms of adult patients with beta thalassemia major and the effect generated by giving antioxidant treatment for 6 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | L-Carnitine and N-acetyl cysteine |
Timeline
- Start date
- 2015-02-01
- Primary completion
- 2017-12-01
- Completion
- 2017-12-01
- First posted
- 2017-01-09
- Last updated
- 2017-01-09
Locations
3 sites across 1 country: Egypt
Source: ClinicalTrials.gov record NCT03014882. Inclusion in this directory is not an endorsement.