Trials / Recruiting
RecruitingNCT03010124
Prognostic and Predictive Biomarkers in Ovarian Cancers
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 350 (estimated)
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris · Academic / Other
- Sex
- Female
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The investigators therefore propose to conduct a biological study of prospectively collected patient tumour samples, ascites, blood and other residual samples (feces, urine, vaginal smear) throughout the disease course where markers (at diagnosis and their change with treatment) will be correlated to outcome in order to investigate how genetic diversity in OC prior to treatment and adaptation following treatment contribute to chemotherapy resistance. In addition freshly collected ascitic samples (and tumour samples) will be subjected to ex vivo DNA repair functional assays and isolated in primary culture (and established as xenografts) for target validation experiments.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Blood sample |
Timeline
- Start date
- 2016-09-26
- Primary completion
- 2030-09-01
- Completion
- 2032-09-01
- First posted
- 2017-01-04
- Last updated
- 2026-03-20
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03010124. Inclusion in this directory is not an endorsement.