Clinical Trials Directory

Trials / Completed

CompletedNCT03008460

Efficacy, Safety and Tolerability of Eziclen®/Izinova® Versus Klean-prep® on Bowel Cleansing in Adolescents Undergoing Colonoscopy

Efficacy, Safety and Tolerability of a Bowel Cleansing Preparation (Eziclen/Izinova®) in Paediatric Subjects Undergoing Colonoscopy: a Phase III, Multicentre, Randomised, Comparative Study Versus Klean-Prep® (PEG-Electrolytes), Administered on the Day Before Colonoscopy, Investigator-blinded, Non-inferiority in Adolescents of 12 to 17 Years of Age (Inclusive) >40 kg

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
250 (actual)
Sponsor
Ipsen · Industry
Sex
All
Age
12 Years – 17 Years
Healthy volunteers
Not accepted

Summary

The purpose of the protocol is to demonstrate that Eziclen®/Izinova®, an osmotic sulphate-based laxative preparation given on the day before colonoscopy has non-inferior efficacy to Klean-Prep® (polyethylene glycol (PEG)-electrolytes) on colon cleansing in adolescents aged 12 to 17 years (inclusive) with a body weight \>40 kg, scheduled to undergo a colonoscopy for a routinely accepted diagnostic indication.

Conditions

Interventions

TypeNameDescription
DRUGEziclen®/Izinova®Oral solution taken the evening before the colonoscopy
DRUGKlean-Prep®Oral solution taken the evening before the colonoscopy

Timeline

Start date
2017-10-15
Primary completion
2020-02-24
Completion
2020-06-29
First posted
2017-01-02
Last updated
2021-03-02
Results posted
2021-03-02

Locations

24 sites across 6 countries: Czechia, France, Germany, Italy, Netherlands, Poland

Source: ClinicalTrials.gov record NCT03008460. Inclusion in this directory is not an endorsement.