NCT03006484

Neurological Outcomes After In-Hospital Cardiac Arrest

Neurological Outcomes After In-hospital Cardiac Arrest: a Prospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 322 (actual)
• Sponsor: Asan Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Little is known about the long-term neurological outcomes after in-hospital cardiac arrest (IHCA). It is also not known whether withdrawal of life-sustaining measures will influence rates of survivors with poor neurological status. Currently, withdrawal of care in comatose patients after cardiac arrest is strongly forbidden by law in Korea. However, a new legislation on allowing withdrawal of care will come into effect since early 2018 in Korea. The investigators aim to determine 1) long-term neurological outcomes in patients who developed IHCA, 2) whether early neurological status can predict late neurological status after IHCA, and 3) whether the proportion of IHCA survivors with good neurological outcomes will change since implementation of new legislation on withdrawal of care.

Detailed description

\<The schedule of assessment\> * Day 0: Neurological examination (First examination will be performed within 2 hours after IHCA) * Day1 - 7: Neurological examination * Day7, 14, 21, 28: Neurological examination, CPC score * Day90: CPC score, survival * Day180: CPC score, survival * Day 360: CPC score, survival \<Cerebral Performance Category(CPC) score\> * CPC 1: good cerebral performance * CPC 2: Moderate cerebral disability(available for independent activities) * CPC 3: Severe cerebral disability(dependent on others for daily support) * CPC 4: Coma or vegetative state * CPC 5: Brain death or death \<Acronyms\> * ACDU(Alert/Confused/Drowsy/Unresponsive) score * FOUR(Full Outline of Unresponsiveness) score

Conditions

• Inhospital Cardiac Arrest

Interventions

Type	Name	Description
OTHER	No intervention	No intervention will be needed.

Timeline

• Start date: 2017-03-21
• Primary completion: 2020-02-03
• Completion: 2020-02-03
• First posted: 2016-12-30
• Last updated: 2020-05-13

Locations

1 site across 1 country: South Korea