NCT03005535

Effects of Corn Oil Plus Vitamin E and B6 on LIpids, PcSk9 and Endothelial Function

Randomised Clinical Trial to Assess the Medium-term Effect of 30 g/Day of a Vitaminised Corn Oil or Olive Oil, on Lipid Parameters, Vascular Risk Markers Blood Pressure and Endothelial Function, in Moderately Hypercholesterolemic Subjects

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 65 (actual)
• Sponsor: University of Bologna · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This will be a randomized clinical trial carried out on subjects with suboptimal control of cholesterolemia who will consume 30 g per day of a vitaminized corn oil (plus B6 and E vitamins), in order to evaluate the effects on lipid profile, endothelial function and PCSK9

Detailed description

In order to assess the mid term effects of vitaminized corn oil on endothelial function and on early markers of functional damage of the arterial wall, moderately hypercholesterolemic subjects will be supplemented for 8 weeks with 30 g/day of both a vitaminized corn oil (plus B6 and E vitamins) or olive oil. The two intervention periods will be spaced by a 4 week washout period.

Conditions

• Atherosclerosis

Interventions

Type	Name	Description
OTHER	Vitaminized corn oil	Oil consumption at the two main meals, lunch and dinner (15gx2 per day)
OTHER	Olive oil	Oil consumption at the two main meals, lunch and dinner (15gx2 per day)

Timeline

• Start date: 2016-10-01
• Primary completion: 2017-02-01
• Completion: 2017-11-01
• First posted: 2016-12-29
• Last updated: 2016-12-29

Locations

1 site across 1 country: Italy