NCT03005353

Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.

Randomized Clinical Trial for Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

Fungal infections have increased over the last two decades, largely because of the increasing size of the population at risk, including patients who are immunocompromised, broad-spectrum antibiotics and intravascular catheter users. Essential oils and other extracts of plants have evoked interest as sources of natural products. They have been shown to possess antibacterial, antifungal, antiviral, insecticidal and antioxidant properties. To the best of our knowledge, no study has examined the efficacy of cumin seed extract on relieving vulvovaginal candidiasis in vivo.

Conditions

• Infection, Fungal

Interventions

Type	Name	Description
DRUG	Cumin seed extract	patients will receive the drug in suppository form
DRUG	clotrimazole	patients will receive the drug in suppository form

Timeline

• Start date: 2018-03-01
• Primary completion: 2019-10-31
• Completion: 2020-01-31
• First posted: 2016-12-29
• Last updated: 2020-06-09

Locations

1 site across 1 country: Egypt