NCT03004963

Bioimpedance-guided Fluid Management in Chronic Peritoneal Dialysis Patients.

Bioimpedance-guided Fluid Management in Chronic Peritoneal Dialysis Patients: A Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 213 (actual)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Peritoneal dialysis (PD) is one of established treatments in the end stage renal disease patients. Volume overload is a predictor of mortality in PD patients. In this Randomized controlled trial, the investigators use the Body Composition Monitor (BCM), a multifrequency bioimpedance device, to measure the level of overhydration in PD patients and explore its value in fluid management in peritoneal dialysis patients as well as their prognosis.

Detailed description

Optimal fluid management is one of the primary objectives of dialysis treatment, and there is significant concern that peritoneal dialysis (PD) patients can become progressively fluid-loaded with time on treatment, especially as residual kidney function declines. Body Composition Monitor (BCM) has the potential to enable better management of fluid balance. The investigators undertake a prospective, randomized, open-label, controlled trial to determine whether availability of longitudinal BCM measures help clinicians maintain stable fluid status over 24 months in 300 peritoneal dialysis patients.

Conditions

• End Stage Renal Disease

Interventions

Type	Name	Description
DEVICE	Body composition monitor	Both body composition monitor (BCM) is used to evaluate the volume status of patients.
DEVICE	clinical indexes	The investigators evaluate the volume status of patients according to clinical indexes.

Timeline

• Start date: 2016-11-01
• Primary completion: 2020-11-01
• Completion: 2020-11-01
• First posted: 2016-12-29
• Last updated: 2024-11-22

Locations

1 site across 1 country: China