NCT03002129

FLuid Responsiveness Prediction Using EXtra Systoles

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University Medical Center Groningen · Academic / Other
• Sex: All
• Age: 19 Years
• Healthy volunteers: Not accepted

Summary

In this study, the investigators propose to investigate a novel technique for fluid responsiveness prediction. It is based on the occurrence of an extra systole, which induces a preload variation: Extra systoles are comprised by, first, the premature/ectopic beat with decreased cardiac preload, then, the post-ectopic beat with moderately increased preload. Consequently, the post ectopic beat is associated with a Frank-Starling curve right shift but is otherwise a normal sinus beat. As such, the post-ectopic beat elucidates and predicts the hemodynamic effect of increasing preload, i.e. giving fluids

Conditions

• Coronary Artery Bypass Graft

Interventions

Type	Name	Description
OTHER	fluid challenge	At two pre-defined time points during the procedure, enrolled patients will receive a fluid bolus of 5 ml/kg during 5 minutes

Timeline

• Start date: 2017-01-01
• Primary completion: 2017-06-26
• Completion: 2017-09-01
• First posted: 2016-12-23
• Last updated: 2018-05-18

Locations

1 site across 1 country: Netherlands