NCT03001843

Ketamine vs Hydromorphone

Does a Ketamine Infusion Decrease Post Operative Narcotic Consumption After Gastric Bypass Surgery?

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will help to determine if investigators can minimize narcotic use in laparoscopic gastric bypass patients while maintaining adequate pain control. This will allow investigators to minimize the negative side effects of narcotics which is a goal in this population.

Detailed description

The study will be a head to head observational study of patients who have undergone gastric bypass surgery. The methods of intraoperative anesthesiology will be Ketamine or Narcotic. Both are FDA approved methods of delivering anesthesia. The amount of narcotics a patient receives is part of the medical record post-operatively will be followed from post-anesthesia care unit (PACU) through to discharge. The amount of narcotics needed to control the patient's pain (converted to morphine equivalent units) and pain scores (a hospital standard measure) will be collected for 48 hours for the study, or until discharge, whichever occurs sooner. The conversion to a morphine equivalent unit allows investigators to compare different narcotics the patient may receive in a more standardized way. The results will be analyzed and compared between the two groups.

Conditions

• Laparoscopic Gastric Bypass
• Obesity
• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	Ketamine	Anesthesia of only Ketamine
DRUG	Narcotics	The narcotic group will receive no ketamine but rather a more standard anesthetic
BEHAVIORAL	pain scale	0-10 pain scale. 0 = no pain and 10 = worst pain

Timeline

• Start date: 2017-02-22
• Primary completion: 2018-12-21
• Completion: 2018-12-21
• First posted: 2016-12-23
• Last updated: 2021-03-09
• Results posted: 2021-03-09

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study