Clinical Trials Directory

Trials / Completed

CompletedNCT03001310

Gene Therapy for Achromatopsia (CNGB3)

An Open Label, Multi-centre, Phase I/II Dose Escalation Trial of a Recombinant Adeno-associated Virus Vector (AAV2/8-hCARp.hCNGB3) for Gene Therapy of Adults and Children With Achromatopsia Owing to Defects in CNGB3

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
23 (actual)
Sponsor
MeiraGTx UK II Ltd · Industry
Sex
All
Age
3 Years
Healthy volunteers
Not accepted

Summary

A clinical trial of AAV - CNGB3 retinal gene therapy for patients with achromatopsia

Detailed description

CNGB3 retinal gene therapy for patients with achromatopsia

Conditions

Interventions

TypeNameDescription
BIOLOGICALAAV - CNGB3Comparison of different dosages of AAV-CNGB3

Timeline

Start date
2017-01-16
Primary completion
2019-10-25
Completion
2019-10-25
First posted
2016-12-23
Last updated
2023-03-08
Results posted
2023-03-08

Locations

2 sites across 2 countries: United States, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03001310. Inclusion in this directory is not an endorsement.