Trials / Unknown
UnknownNCT03001271
Acute Effect of Agiotensin-(1-7) in Healthy and Hypertensive Subjects
Acute Effect of Agiotensin-(1-7) on Bood Pressure and Heart Rate in Healthy and Hypertensive Subjects
- Status
- Unknown
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 32 (estimated)
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
In the modern concept of Renin-angiotensin System, Angiotensin-(1-7) plays a key role and demonstrates promising therapeutic potential due to it is generally opposite effects to Angiotensin II. The aim is to evaluate the effect of Ang-(1-7) acute administration on systolic and diastolic blood pressure (SBP and DBP) and heart rate (HR) in healthy and hypertensive subjects.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Angiotensin 1-7 | |
| OTHER | Placebo |
Timeline
- Start date
- 2014-01-01
- Primary completion
- 2017-02-01
- Completion
- 2017-03-01
- First posted
- 2016-12-23
- Last updated
- 2016-12-23
Source: ClinicalTrials.gov record NCT03001271. Inclusion in this directory is not an endorsement.