Clinical Trials Directory

Trials / Completed

CompletedNCT03001076

Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)

A Randomized, Double-Blind, Placebo-Controlled, Parallel Group, Multicenter Study to Evaluate the Efficacy and Safety of Bempedoic Acid (ETC 1002) 180 mg/Day as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
269 (actual)
Sponsor
Esperion Therapeutics, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if bempedoic acid (ETC-1002) added-on to ezetimibe therapy is effective and safe versus placebo in patients with elevated LDL cholesterol.

Conditions

Interventions

TypeNameDescription
DRUGBempedoic acidbempedoic acid 180 mg tablet
DRUGEzetimibeezetimibe 10 mg tablet
OTHERPlacebomatching placebo tablet

Timeline

Start date
2016-11-29
Primary completion
2018-01-11
Completion
2018-02-12
First posted
2016-12-22
Last updated
2020-05-11
Results posted
2020-04-03

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03001076. Inclusion in this directory is not an endorsement.