NCT02999321

The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 93 (actual)
• Sponsor: Purdue University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Assess the impact of chronic use of aspartame on glycemia, appetite and body composition.

Detailed description

Participants will be randomly assigned to one of three parallel arms: 0% (water), 5 mg, 15mg aspartame. Participants will have an oral glucose tolerance test at the beginning and end of a 12 week intervention. . Participants will report to the lab weekly for 12 weeks to pick up their next week's intervention products and measurements for body weight, waist circumference, blood pressure and heart rate. They will consume their intervention products daily for 12 weeks. They will record appetite sensations and collect a 24 hour urine sample at weeks 0, 4, 8, and 12.

Conditions

• Oral Glucose Tolerance

Interventions

Type	Name	Description
OTHER	aspartame	will be given 5mg aspartame or 15 mg aspartame
OTHER	water	control group

Timeline

• Start date: 2016-08-17
• Primary completion: 2017-05-05
• Completion: 2017-05-05
• First posted: 2016-12-21
• Last updated: 2018-01-18

Locations

1 site across 1 country: United States